Shinichirou Nakagami was living the life other boys from his grade could only dream of—staying under the same roof as prodigal student Hiromi Yuasa. However, the bright and cheerful Hiromi has been depressed and cold at home ever since her mother passed away. While he is the subject of the ignorant jealousy of his peers, rumors begin to spread when Shinichirou meets Noe Isurugi—a girl known for cursing classmates, curses which always end up becoming reality. Noe curses Shinichirou as well, but two pits are created when you curse someone, and her curse on Shinichirou comes back to bite her in the form of a raccoon to her beloved chicken, Raigomaru. Despite this, she does not shed a single tear; Noe had had her tears stolen. For Noe to be able to cry again, she would need the tears of another, and Shinichirou knows a person whose tears he wants to take away.

Millie Nocturne has one great goal in life: to be the best in the universe - at absolutely everything! But when she tries her hand at being the "best detective," she ends up an unwilling partner with two people who will change her life forever: Kane Blueriver, the psi-blade-wielding master of the starship Swordbreaker, and Canal, the smart-mouthed holographic image of the ship's computer. Join this unlikely trio on their adventures as they hurtle through space facing off against intergalactic crime lords, rogue starships, and hijackers dressed as chickens... and that's just the tip of the asteroid!

In ancient times, some witches married their familiars, who had taken human form, giving birth to a lineage of ogres. One such ogre is Morihito Otogi, who while appearing completely human, still retains the inhuman strength of his bloodline. Nico Wakatsuki is a young witch and Morihito's childhood friend, but as part of her education, she had to go to the Witches' Holy Land to train and part ways with Morihito . Years later, just before Morihito's first year of high school, Nico returns home with one goal in mind: to claim him as her familiar. While most witches choose a cat or a bat, Nico has her heart set on Morihito in more ways than one. Although seemingly oblivious to her true feelings, Morihito and Nico end up living together under the same roof with both of Morihito's parents elsewhere. While reluctant at first, Morihito accepts his new role, determined to help Nico seamlessly fit back in with human society and protect her from fated disaster.

Marin is a typical junior high school girl with a sunny disposition and a loving adoptive family. Her life takes a drastic change when a mysterious mirage is seen in the sky above the entire earth. Killer androids called Monomakia descend to earth from the formation in the sky called Brigadoon and begin to hunt down little Marin. She discovers a blue bottle in a shrine as she seeks escape and from the bottle comes a protector, a sword carrying gun slinging alien called Melan Blue, together they must save the earth and deal with family crisis, school prejudice and the police and come to an understanding of Marins past and Melans unexplained mission, as well as learn to trust each other. Set in 1969 Japan with a colorful cast of friends and enemies.