Now in possession of the Edens Zero, Shiki Granbell has gathered the Four Shining Stars. With the help of his new friends, Shiki will be able to breach Dragonfall—the border of the Sakura Cosmos swarming with mechanical dragons. Once that is achieved, he can continue his quest to find the goddess Mother. Before the Edens Zero crew can advance their journey, they notice a mysterious warship following them. Upon learning that the ship—the Belial Gore—belongs to Drakken Joe, Shiki and his crew attempt to infiltrate it, intent on figuring out why the Dark Alchemist is after them. In the process, the Edens Zero is taken hostage by Drakken's subordinates. Though they are in a tight situation, Shiki refuses to back down. Working together with his friends, Shiki will have to take down the Dark Alchemist if he hopes to make it out of the Belial Gore alive.

In nineteenth-century France, humans and vampires coexist. The young vampire Noé is traveling to Paris in search of The Book of Vanitas, which is said to be capable of unleashing a curse upon all vampires. On an airship, he finds himself embroiled in a strange incident. It is Vanitas, a human calling himself a vampire expert, who appears before Noé in the ensuing chaos. In Vanitas’s hands is the very book that Noé has been searching for: The Book of Vanitas… Following this encounter, the curtain is set to rise on this tale of vampires, curses, and salvation…

On a rainy afternoon, a male high school student awakens freezing on the streets with no memory of how he got there. His classmate and crush, Karen Inukai, finds him and takes him back to her home where, to his surprise, she starts to undress. She seems intent on bathing with him, though he has no idea why. When she holds him once more, he catches a glimpse of himself in the mirror—discovering that he has turned into a dog! Inukai adopts the puppy and names him Pochita. Now, he must adjust to life as a dog and figure out how to get out of this strange predicament. But while he mulls over an escape plan, Pochita sees a whole new side to Inukai that he never saw at school.

One day, on his way to visit his grandfather's grave, Zhang Chulan is attacked by zombies in a graveyard. In the midst of that situation, he is saved by a mysterious girl, who wields kitchen knives in order to kill the enemies. The girl tells Chulan, who is relieved, to face his hardships head on and leaves. However, Chulan later sees that girl again at his university. From that moment, Zhang Chulan's destiny begins to move. There will be strangers with special powers appearing one by one, with battles involving those abilities. Each episode will bring a new mystery to light.